I think there are times when you have to choose between right and wrong , moral and immoral , good and evil. I don't see any mind boggling chemistry between Shaira-Azaan but wanting them to end up together is what feels right. Noor is a terrible character and she does not deserve any sort of sympathy/love from neither Azaan nor Shaira.
So in case of Azaan-Noor given the circumstances no matter the amount of chemistry , physics , statistics , i would never want them to end up together.
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