Has anyone ever taken a Paracetamol or Tylenol? Just FYI. Maybe you should refrain from this as well.
Adverse Reactions
The following adverse drug reactions and incidences are derived from product labeling unless otherwise specified.
Oral, Rectal: Frequency not defined:
Dermatologic: Erythema of skin, skin blister, skin rash
Otic: Hearing loss
IV:
>10%: Gastrointestinal: Nausea (adults: 34%; neonates, infants, children, and adolescents: ≥5%), vomiting (adults: 15%; neonates, infants, children, and adolescents: ≥5%)
1% to 10%:
Cardiovascular: Hypertension, hypotension, peripheral edema (adults)
Dermatologic: Pruritus (neonates, infants, children, and adolescents: ≥5%)
Endocrine & metabolic: Hypoalbuminemia (neonates, infants, children, and adolescents), hypokalemia, hypomagnesemia (neonates, infants, children, and adolescents), hypophosphatemia (neonates, infants, children, and adolescents)
Gastrointestinal: Constipation (neonates, infants, children, and adolescents: ≥5%), diarrhea (neonates, infants, children, and adolescents)
Genitourinary: Oliguria (neonates, infants, children, and adolescents)
Hematologic & oncologic: Anemia
Hepatic: Increased serum aspartate aminotransferase (Watkins 2006)
Local: Infusion-site pain, pain at injection site
Nervous system: Agitation (neonates, infants, children, and adolescents), anxiety (adults), fatigue (adults), headache, insomnia (adults: 7%), trismus (adults)
Neuromuscular & skeletal: Muscle spasm (≥1%)
Respiratory: Abnormal breath sounds (adults), atelectasis (neonates, infants, children, and adolescents), dyspnea (adults), pleural effusion (neonates, infants, children, and adolescents), pulmonary edema (neonates, infants, children, and adolescents), stridor (adults), wheezing (adults)
Postmarketing (all formulations):
Dermatologic: Acute generalized exanthematous pustulosis (FDA 2016), Stevens-Johnson syndrome (FDA 2016), toxic epidermal necrolysis (Watanabe 2016; FDA 2016)
Hepatic: Acute hepatic failure, hepatotoxicity (Ramachandran 2019, Yoon 2016), increased serum alanine aminotransferase (Watkins 2006)
Hypersensitivity: Anaphylaxis (Ho 2008, Numata 2016), hypersensitivity reaction (Thomspon 2019)