Gappa Tappa corner thread 11 - general discussions - Page 36

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mishkil88 thumbnail
Posted: 5 years ago

Originally posted by: Dhanusg

i would support human trials for vaccine before it is approved for human use animal trials are not enough.
all vaccines have to undergo phases of trial before it can be given for mass immunisation.
If you know before we give flu vaccine we have to ask few questions like any egg allergies , preexisting fever, history of any neurological disorders like guillian - barre as it can be very dangerous

Though we can recommend recombinant Flu vaccine with egg allergies above 18

Only scientists and physicians know how rigorous n tedious Process it is and possible adverse reactions.


so its better to wait than to rush. In medicine 1st oath we take is Do no Harm then rest.


rotavirus vaccine is a routine immunisation schedule for infants here in usa.
i remember in india during my med school time rotavirus, mmr , hepatitis a, pcv were not routine vaccines for kids in india.
Since mmr is live vaccine we cannot give in immunocompromised individuals like scid, hiv etc

mishkil88 thumbnail
Posted: 5 years ago

Originally posted by: Dhanusg

i would support human trials for vaccine before it is approved for human use animal trials are not enough.
all vaccines have to undergo phases of trial before it can be given for mass immunisation.
If you know before we give flu vaccine we have to ask few questions like any egg allergies , preexisting fever, history of any neurological disorders like guillian - barre as it can be very dangerous

Though we can recommend recombinant Flu vaccine with egg allergies above 18

Only scientists and physicians know how rigorous n tedious Process it is and possible adverse reactions.


so its better to wait than to rush. In medicine 1st oath we take is Do no Harm then rest.


rotavirus vaccine is a routine immunisation schedule for infants here in usa.
i remember in india during my med school time rotavirus, mmr , hepatitis a, pcv were not routine vaccines for kids in india.
Since mmr is live vaccine we cannot give in immunocompromised individuals like scid, hiv etc

4 cycles of human trials will be conducted between 7th July to 15th Aug. This time is too short. So some people are objecting.
Dhanusg thumbnail
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Posted: 5 years ago

Originally posted by: mishkil88

4 cycles of human trials will be conducted between 7th July to 15th Aug. This time is too short. So some people are objecting.

Yes it is too fast to find if vaccine can be used for mass immunisation. Safety and efficacy of vaccine without adequate time is concerning.

kamalsh56 thumbnail
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Posted: 5 years ago

Originally posted by: Dhanusg

Yes it is too fast to find if vaccine can be used for mass immunisation. Safety and efficacy of vaccine without adequate time is concerning.

My guess is they know it is not possible to meet that deadline but probably they want to keep the notorious system under pressure or if they announce a 12 month period they may not start work at trials at all.

Hope that doesn't result in cooking up results to satisfy them.

kamalsh56 thumbnail
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Posted: 5 years ago

As I guessed, the reason that I mentioned has just been clarified by ICMR:


"Just as red tape was not allowed to become a hindrance in the fast track approval of new indigenous testing kits or for introducing in the Indian market potential COVID-19 related drugs, the indigenous vaccine development process has also been sought to be insulated from slow file movement. The aim is to complete these phases at the earliest, so that population-based trials for efficacy could be initiated without delay," it said.

"ICMR's process is exactly in accordance with the globally accepted norms to fast-track the vaccine development for diseases of pandemic potential wherein human and animal trials can continue in parallel," the agency said.

The vaccine trials will be done following the best practices and rigour, and will be reviewed, as required, by a Data Safety Monitoring Board (DSMB), ICMR said."

iluvusakshi thumbnail
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Posted: 5 years ago

कसला मजबूत पाऊस पडतो आहे . काल पासून लागलाय.

कॉरोना मूळे कुठे जाता येत नाहीये. नाहीतर मस्त भिजायला गेलो असतो friends आणि फॅमिली बरोबर.

या वर्षी असाच जाणार का पावसाळा.... न भिजता..या कॉरोना मुळे😒

RPRRR42 thumbnail
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Posted: 5 years ago

evadha lockdown kela ahe sagalikade parat,tari cases vadhatach ahet.

ata kai reason detil ki daily test cha no vadhavala mhanun cases vadhat ahet.karan ata lok rules follow karat nahit asa sangata yenar nahi na.karan kal ani aaj pavasamule lok gharabaher kahrach khoop kami gele ahet.even kahi offices madhe suddha lok gele navhate.

tari aaj maharashtrat no cases above 7000.

yanchi fakta reasons tevadhi badalatat.

khar kai khot kai ,kahich kalt nahi.

sagala savala gondhal chalu ahe.

tikade us madhe tar last 3 days,kahar ahe.tar trump mast us independence day celebrate karat ahe.

just think ,hech modini kel asta tar kai gahajab zala asta.

mishkil88 thumbnail
Posted: 5 years ago

Originally posted by: RPRRR42

evadha lockdown kela ahe sagalikade parat,tari cases vadhatach ahet.

ata kai reason detil ki daily test cha no vadhavala mhanun cases vadhat ahet.karan ata lok rules follow karat nahit asa sangata yenar nahi na.karan kal ani aaj pavasamule lok gharabaher kahrach khoop kami gele ahet.even kahi offices madhe suddha lok gele navhate.

tari aaj maharashtrat no cases above 7000.

yanchi fakta reasons tevadhi badalatat.

khar kai khot kai ,kahich kalt nahi.

sagala savala gondhal chalu ahe.

tikade us madhe tar last 3 days,kahar ahe.tar trump mast us independence day celebrate karat ahe.

just think ,hech modini kel asta tar kai gahajab zala asta.

Thane dombivali Kalyan madhe 2 july-12 July asa lockdown declare kela tevha aadhiche 2 diwas dukananmadhe lokani evadhi gardi keli ki vicharu naka. Corona vadhnar nahitar kay ...nantar lockdown samplyavar pan Lok ashich gardi kartil. Roj thodavel tari grocery ani vegetables chi dukane chalu thevayla pahije hoti.
Edited by mishkil88 - 5 years ago
iluvusakshi thumbnail
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Posted: 5 years ago

Amchya ikde tar saglich boamb ahe. Grocery shops ani vegetables vendors pan nahit.

Sagla band. Sagar karande chya puneri bai pramane sangaycha zala tar ...'BAND MHANJE BAND'

Dhanusg thumbnail
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Posted: 5 years ago

Originally posted by: RPRRR42

evadha lockdown kela ahe sagalikade parat,tari cases vadhatach ahet.

ata kai reason detil ki daily test cha no vadhavala mhanun cases vadhat ahet.karan ata lok rules follow karat nahit asa sangata yenar nahi na.karan kal ani aaj pavasamule lok gharabaher kahrach khoop kami gele ahet.even kahi offices madhe suddha lok gele navhate.

tari aaj maharashtrat no cases above 7000.

yanchi fakta reasons tevadhi badalatat.

khar kai khot kai ,kahich kalt nahi.

sagala savala gondhal chalu ahe.

tikade us madhe tar last 3 days,kahar ahe.tar trump mast us independence day celebrate karat ahe.

just think ,hech modini kel asta tar kai gahajab zala asta.

As u know every virus mutates spontaneously with passing time and so becomes difficult to treat as compared to bacteria which respond to specific antibiotics so now the report says that corona virus has now mutated again to make it more infectious but less potent. So this explains rapid spread but not as lethal.

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Posted by: mishkil88 · 1 years ago

Here is new thread for general chit-chat. Happy posting.

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Posted by: Prateekshaa29 · 5 months ago

So thread 9 here used tis after we finish 8

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Posted by: md410 · 5 months ago

Hey guys here is the thread 3 please move here when previous one reaches at 150 limit

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Posted by: mishkil88 · 4 months ago

New thread opened. Please post here.

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Posted by: mishkil88 · 2 years ago

Hello friends, please start posting on this new thread now.

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