Actually major plot change will happen beacuse as of the current plot we have more of the equation between suhana and kalayani and the mystery that follows and some tashan between malhar and mahathre
Pillu anyway will require less sequence like atleast until they show his transplant or recovery they can keep showing some stills of pillu shot from arzans home and adjust with some editing techniques ( like we have seen in certain seens before ) as far as he is suffering from illness pillus scene can be infact kept less.
But here the story at mathre's track cannot be taken forward without suhana because it is she who is to be used to make kalayni come back everyday to triloks net.
The actress playing suhana is also a small kid obviously she can't come and shoot and unlike pillu who is toddler her scenes cannot be adjusted or edited like the does sometimes for moksh. Like in moksh case we see kalma talking to moksh in stroller it is not necessary that moksh is in the stroller they can edit and input some pillus old scenes of him on stroller and they can also use the dummy doll clad in clothes like when they did to befool ahir
So I am feeling postive pata nahi kyom that they will have to delay or remove this mahathre and suhanas track but can't trust cvs they might find a way out too. But I feel some hope that as rules exist they will take some different route.