Gappa Tappa corner thread 11 - general discussions - Page 35

Originally posted by: NerdyMukta

@kamalsh-from news sources here, it's seems that pre-clinical studies are done. And human trials are underway. They have yet to determine if the vaccine is efficacious. Safety and immune response data shows promise. Is that accurate?

देव त्यांच्या प्रयत्नांना यश देवो.फक्त त्यात नि:स्वार्थ,निरपेक्ष विचार असावा.कसली शर्यत नको,राजकारण नको.मानवजातीच कल्याण हा एक आणि एकच निकष असावा.

Laav re to video baghitla. Kay bekaaar program aahe. Lockdown madhye ek se ek faltu program banvlet. Nilesh sable producer aslyane satat tyacha chehra tyane screen var dakhavlay. Participants perform karat astana pan ardha screen tyacha chehra asto.

Originally posted by: NerdyMukta

@kamalsh-from news sources here, it's seems that pre-clinical studies are done. And human trials are underway. They have yet to determine if the vaccine is efficacious. Safety and immune response data shows promise. Is that accurate?

Yes. Supposedly, animal trials have been found to be successful in building antibodies. Only problem is, in many cases, an animal response does not guarantee a similar response in humans. Biggest point that needs to be verified is human safety with varying dosages. If they find there are no safety issues, they may decide to go ahead for full scale production as soon as some preliminary results show at least some form of antibodies response.

It could risk failure in terms of efficacy but in present situation where all are clutching at straws, they may take a chance if there are no safety issues. As it is, world has tried out things like HCQ, Remdesivir, Dexamethasone etc. just on the basis of a few trials.

Keeping fingers crossed that it may hit bullseye.

Originally posted by: mishkil88

Laav re to video baghitla. Kay bekaaar program aahe. Lockdown madhye ek se ek faltu program banvlet. Nilesh sable producer aslyane satat tyacha chehra tyane screen var dakhavlay. Participants perform karat astana pan ardha screen tyacha chehra asto.

Me adhi sangitlya pramane, mala tar te saglech tik tok che videos vatatat, je aplyala ya lockdown madhe fb or whats app var already alele hote.

Ani yes. I agree with u. It is a very bekkar programme.

Watched the Hindi movie Junglee (yes, as it happens to be Pooja Sawant's first foray into Bollywood).It is a total Hollywood/Bollywood potboiler (most of the technical specialists seem to be from the Hollywood action scene). The story is about Vidyut Jamwal, supposedly a vet (but who looks more like a full time body builder) who is out to eliminate a group of elephant poachers in an elephant reserve. It is an out and out vehicle to highlight Vidyut's body/stunts/martial arts prowess. He does his stunts at the drop of a hat ( and many a time even when there is no hat dropped). Hardly any role for Pooja (but she valiantly carries on to give her best) in this all action movie. Just a one time watch for only those who like slick stunt movies.

Interesting piece of information for those who are doubting the Indian vaccine:

"In the past, Bharat Biotech has manufactured the H1N1 vaccine during the swine flu outbreak and has over 140 global patents and 16 vaccines in its portfolio. The most significant of their developments is arguably the rotavirus vaccine Rotavac, a next-gen vaccine against viral gastroenteritis that got pre-approval from the WHO after an Oxford laboratory found it safe and efficacious."

So we can certainly keep our fingers crossed.

New web series on hotstar.. 'aarya'

Starring sushmita sen, chandarchood, sikander kher .

Review and ratings are good.

Here is the review by you tuber: deeksha sharma

https://youtu.be/T-K7RpJqxOI

Originally posted by: kamalsh56

Interesting piece of information for those who are doubting the Indian vaccine:

"In the past, Bharat Biotech has manufactured the H1N1 vaccine during the swine flu outbreak and has over 140 global patents and 16 vaccines in its portfolio. The most significant of their developments is arguably the rotavirus vaccine Rotavac, a next-gen vaccine against viral gastroenteritis that got pre-approval from the WHO after an Oxford laboratory found it safe and efficacious."

So we can certainly keep our fingers crossed.

I really hope n pray for the success of this vaccine.

Till Today one lakh patients of Maharashtra have been cured from corona. 👍🏼

Originally posted by: kamalsh56

Yes. Supposedly, animal trials have been found to be successful in building antibodies. Only problem is, in many cases, an animal response does not guarantee a similar response in humans. Biggest point that needs to be verified is human safety with varying dosages. If they find there are no safety issues, they may decide to go ahead for full scale production as soon as some preliminary results show at least some form of antibodies response.

It could risk failure in terms of efficacy but in present situation where all are clutching at straws, they may take a chance if there are no safety issues. As it is, world has tried out things like HCQ, Remdesivir, Dexamethasone etc. just on the basis of a few trials.

Keeping fingers crossed that it may hit bullseye.

i would support human trials for vaccine before it is approved for human use animal trials are not enough.
all vaccines have to undergo phases of trial before it can be given for mass immunisation.
If you know before we give flu vaccine we have to ask few questions like any egg allergies , preexisting fever, history of any neurological disorders like guillian - barre as it can be very dangerous

Though we can recommend recombinant Flu vaccine with egg allergies above 18

Only scientists and physicians know how rigorous n tedious Process it is and possible adverse reactions.

so its better to wait than to rush. In medicine 1st oath we take is Do no Harm then rest.

rotavirus vaccine is a routine immunisation schedule for infants here in usa.
i remember in india during my med school time rotavirus, mmr , hepatitis a, pcv were not routine vaccines for kids in india.
Since mmr is live vaccine we cannot give in immunocompromised individuals like scid, hiv etc